We’re talking about a paradigm shift because, until now, horizontal transfer has been seen as very rare in animal species. It’s actually a lot more common than we think. It’s like a pandemic, and one that can infect species that weren’t genetically or geographically close. It’s puzzling, scary almost,“ Cédric Feschotte of the University of Texas
Foreign genetic elements have integrated themselves into the genomes of several mammalian and reptilian species via horizontal transfer, rather than by traditional vertical inheritance, according to a recent study.
Cédric Feschotte of the Univesrsity of Texas at Arlington and colleagues discovered previously uncharacterized elements of the hAT (hobo/Activator/Tam3) transposon superfamily, which they dubbed “space invaders.” Feschotte says that what he calls space invader tranposons jumped sideways millions of years ago into several species by piggybacking onto a virus.
The team thinks that the hAT transposon invasion occurred about 30 million years ago and spread across at least two continents. “It’s like a pandemic, and one that can infect species that weren’t genetically or geographically close. It’s puzzling, scary almost,” Feschotte said in an interview with New Science.
In most organisms, genes are inherited or passed along from parent to offspring. Lateral or horizontal transfer of genetic information, which is central to the evolution of simple prokaryotic organisms, occurs when non-native genetic elements incorporate themselves into a host genome. These elements are typically delivered via viruses, circular loops of DNA called plasmids, or transposons, which are small sequences of mobile DNA.
The researchers discovered the elements while surveying DNA transposons in the bushbaby, a nocturnal primate, and, after further examination, found the invaders in other species, including rats and mice, opossum, and the African clawed frog. Space invaders were not present, however, in the genomes of many other vertebrate species. These infiltrations, the authors say, are the first report of horizontal transfers of transposons in mammalian species, and likely occurred around the same time frame in affected species approximately 15 to 46 million years ago.
http://www.dailygalaxy.com/my_weblog/2009/05/space-invaders.html#more
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